Urinalysis and chronic kidney disease
(Aotea News, December 2010)
Anatomic & General Pathologist
Urinalysis is an important test for screening and investigating chronic kidney disease (CKD).
- Recent bpac guidelines (July 2009) recommend the testing, where appropriate, of mid-stream urine (MSU) for red blood cell casts or dysmorphic red cells.
- Please write “casts/dysmorphic RBC” on the request form to ensure that we know to carry out this test.
We are also changing the ranges for RBC in urine:
- The most important change is to the lowest reported value (currently < 25 x 10 6 /L) to < 10 x 10 6 /L, a value currently accepted as normal.
- Further groupings of abnormal resultswill be similarwith values of 11-100, 101-500 and >500
Urinalysis for CKD also involves detection of proteinuria:
The recommended testing for proteinuria is albumin creatinine ratio (i.e. urine microalbumin) or protein creatinine ratio.
- Protein creatinine ratio is more appropriate for non-diabetic patients at risk of CKD.
- To ensure the correct test is performed please note on the request form:
Urine microalbumin or